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Sleepwalking has been described in medical literature dating before Hippocrates (460 BC-370 BC).In Shakespeare's tragic play, Macbeth, Lady Macbeth's famous sleepwalking scene ("out, damned spot") is ascribed to her guilt and resulting insanity as a consequence of her involvement in the murder of her father-in-law. Stages 1, 2, and 3 are characterized as non-rapid eye movement (NREM) sleep.A person with bipolar disorder has a condition that is linked to chemical imbalances in the brain.

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If sleepwalking is caused by underlying medical conditions, for example, gastroesophageal reflux, obstructive sleep apnea, periodic leg movements (restless legs syndrome), or seizures, the underlying medical condition should be treated.

Medications for the treatment of sleepwalking disorder may be necessary in the following situations: Benzodiazepines, such as estazolam (Pro Som), or tricyclic antidepressants, such as trazodone (Desyrel), have been shown to be useful.

In most cases, no treatment is necessary because sleepwalking rarely indicates any serious underlying medical or psychiatric problem.

In most children, sleepwalking disappears at puberty.

Sleepwalking, night terrors, and confusional arousals are all common non-REM sleep disorders that tend to overlap in some of their symptoms.

A percentage of young children through mid adolescence will experience some or all of these behaviors.Sleep deprivation, chaotic sleep schedules, fever, stress, magnesium deficiency, and alcohol intoxication can trigger sleepwalking.Drugs, for example, sedative/hypnotics (drugs that promote sleep), neuroleptics (drugs used to treat psychosis), minor tranquilizers (drugs that produce a calming effect), stimulants (drugs that increase activity), and antihistamines (drugs used to treat symptoms of allergy) can cause sleepwalking.Thus the average person experiences 4-5 complete sleep cycles per night.Sleepwalking occurs more frequently in identical twins, and is 10 times more likely to occur if a first-degree relative has a history of sleepwalking.Occasionally, the frequency of episodes increases briefly after discontinuing the medication.

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